Since the World Health Organization has recommended Bacillus Calmette-Gu?in (BCG) vaccination as a prat of the Global Expanded Program for immunization in areas where tuberculosis is endemic, BCG immunization at neonate is still the basic method
for
tuberculosis prevention in Korea. The most common complication of BCG vccination in normal immunocompetent children are local and regional lymphadenitis. An outbreak of axillary and/or supraclavicular lymphadenitis after BCG vacccination has been
bserved in all of 50 infants and these were treated from january 1992 to December 1993. To assess factors affecting clinical course and therapeutic consequence of BCG related lymphadenits, we analized clinical laboratory and treatment outcome.
@ES The results are as follows:
@EN 1) The most prevalent age group in fifty cases was 15 weeks group, and male to female ratio was 28 : 22(1.3 : 1)
2) The most prevalent site of the lesion was ipsilateral axilla and the rest was ipsilateral supraclavicle.
3) Palpable node was the most common finding and the main reason to visit hospital.
4) Patient with pulmonary tuberculosis was detected in only one.
5) The diagnostic methods consist of local finding, AFB staining on aspiration smear, PPD skin test, blood PcR, and histologic finding on lymph node biopsy. Among them, PPD skin test and blood PCR were significantly correlated with the period
for
wound
healing.
6) The therapeutic modalities were classified as follows: Group I: INH therapy only, Group II; incision and drainage only. Group III; incision and drainage with INH therapy, and Group IV; Wede excision and INH therapy. The operative procedures
were
performed by incision and drainage(88%), and wide excision(6%). Three cases were operated under the general anesthesia and forty-two cases were local.
7) The most common pathologic finding was chronic granulomatous inflamation(68%).
8) INH medication was given to the 45 patients(90%). Mean duration of anti-tuberculous me dication was 4 months.
9) In regard to the period for wound healing, no difference was observed between the INH medication group and non-medicated group.
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